Methylprednisolone as an alternative therapy for Kawasaki disease: case series
نویسندگان
چکیده
منابع مشابه
Adverse effects of methylprednisolone pulse therapy in refractory Kawasaki disease.
The efficacy and safety, including arrhythmia and sudden death, 2 of intravenous methylprednisolone pulse (IVMP) therapy in patients with Kawasaki disease (KD) are uncertain. We conducted a control study in KD patients with persistent or recurrent fever (>37.5̊ C) 48 hours after a single infusion of initial intravenous immunoglobulin (IVIG) 2 g/kg. At enrolment (day 1), the subjects were randomi...
متن کاملTriptolide as an Alternative to IVIG Therapy for Kawasaki Disease in a Mouse Model.
BACKGROUND Kawasaki disease is treated by immunoglobulin therapy, which has adverse side effects like renal damage. AIMS The aim of the present study was to explore the effectiveness of triptolide, a compound derived from threewingnut that has anti-inflammatory effects, on the treatment of Kawasaki disease in a mouse model. STUDY DESIGN Animal experiment. METHODS A mouse model of Kawasaki...
متن کاملForever interesting disease: Kawasaki vasculitis – case series
Results Youngest patient was 3 months, oldest 13 years, far more boys 83% (5/6). Seasonal peak was during winter (Jan-Feb) in 50%. Clinicall presentation (figure 2) was consistent with literature. All patient had high inflammatory markers, anemia (patients 1, 2, 5), thrombocitosis. Patient 1. had incomplete KD, with coronary artery aneurisms seen before therapy. Completely responded well to one...
متن کاملMethylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease.
Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse ster...
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Kawasaki disease is a systemic vasculitis of children. Among gastrointestinal symptoms of this disease jaundice occurs uncommonly. We present a 23 month boy with icter and clinical hepatitis and final diagnosis of kawasaki disease.
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ژورنال
عنوان ژورنال: Paediatrica Indonesiana
سال: 2020
ISSN: 2338-476X,0030-9311
DOI: 10.14238/pi60.5.2020.283-6